This presentation first discusses the limitations of offline microscopy including:
- Long time delays between sampling and viewing images
- Difficulty viewing particles in pressurized, explosive or toxic systems
- A lack of confidence in results since particles - in particular crystals and droplets - can change when sampled
- Inability to acquire enough offline images, at the right time, to provide useful process understanding
This webinar introduces new probe-based technology utilizing real-time microscopy that now allows you to visualize particles and particle mechanisms as they exist in process. Applications include:
- Directly observing critical crystallization mechanisms:
- Seeding
- Growth
- Nucleation
- Agglomeration
- Breakage
- Viewing how droplet size changes in real time under real process conditions
- Identifying unexpected process events such as shape or phase changes
- Evaluating process conditions to target a specific particle size and shape distribution
By viewing particles as they exist in process, scientists become more effective at making high-quality, low-risk, evidence-based decisions that support cost effective optimization, scale-up and control.