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For pharmaceutical and biopharma manufacturers, sanitization of water systems and distribution loops is critical for maintaining the quality of the water used to produce products.
Historically, sanitization has been performed using chemicals or heat, but the use of ozone is increasing due to several benefits. The use of on-line ozone sensors permits not only the control of proper ozone levels for sanitization, but also compliance with the “no added substance” rule of the global pharmacopeias.
This document looks at three considerations for switching to ozone:
- Destroys organics and biofilm more effectively than chlorine
- Leaves no residual material and decays to harmless oxygen
- More effective than chemicals and more economical than thermal sanitization
METTLER TOLEDO Thornton’s pureO3™ ozone sensor provides fast and reliable ozone monitoring down to zero ppb, allowing confirmation of the decay of ozone to oxygen and that the proper ozone level required for system sanitization is reached. The sensor’s ppb-level monitoring capability provides a clear indication that the pharmacopeias’ “no added substance” rule is met and that the pharmaceutical water is ready for use.
