Multicolumn Chromatography (MCC) is an advanced technique designed for the efficient purification of monoclonal antibodies in biopharmaceutical manufacturing. Unlike traditional single-column methods, MCC uses multiple smaller columns in a cyclical fashion, which enhances productivity and throughput. This approach optimizes resin utilization, allowing for quicker binding of monoclonal antibodies while reducing resin requirements. Operating continuously, MCC is ideal for large-scale production, ensuring consistent output. Its adoption in the biopharmaceutical industry is rising due to increased productivity and lower operational costs, all while maintaining high quality standards