Utbildning

Microbial Analysis with the 7000RMS

Studies and testing to show its response to multiple microorganisms

The 7000RMS™ is an on-line instrument for real-time microbial analysis of pharmaceutical waters. This on-demand webinar looks at how efficiently the 7000RMS responds to specific microorganisms.

The presenter explains:

  • How the 7000RMS detects and counts microorganisms
  • Studies to show how the analyzer is able to detect microorganisms
  • Results from a case study to show process control benefits of on-line microbial analysis

Improve process control with the 7000RMS for real-time microbial analysis in your water system. Studies have shown that the analyzer can effectively detect different varieties of water-related microorganisms in various concentrations.

Microbial contamination monitoring in pharmaceutical-grade waters has relied on laboratory-based methods developed over a century ago. These are labor-intensive techniques that require lab personnel to take samples manually from sampling ports. The samples are then cultured on a plate to determine if any colonies form that indicate microbial contamination. This method has a number of potential sources of contamination, even when handled by highly-skilled personnel. This type of contamination can result in false positive readings, which then lead to additional testing expenses, costly investigations and, as a worst case, scrapping of the production batch even though it is not truly contaminated.

An alternative to laboratory-based techniques that is gaining wide acceptance from regulators and the industry, is rapid microbial methods (RMMs). These are real-time, on-line technologies for determining bioburden in a sample.

The 7000RMS is an on-line water bioburden analyzer for real-time measurements of microbial contamination in pharmaceutical waters. This at-line analyzer offers a rapid microbial method solution for controlling water systems.

Real-time Microbial Detection
The 7000RMS delivers continuous monitoring of water with results every two seconds. It requires no sample preparation or incubation period.

Accurate Counting of Microorganisms
Advanced laser-induced fluorescence and Mie scattering technologies are used to count microorganisms present in pharmaceutical grade water systems.

Improves Process Control
The analyzer provides a history of trends in your water system prior to an out-of-specification event, helping to find the root cause of contamination.

Presenter: Arundhati Samanta. Global Product Manager Microbial Detection has over 12 years' experience in product and market management.