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Application note on the determination of the melting point of caffeine |
Caffeine is the most widely consumed psychoactive drug in the world. Apart from coffee, caffeine can be found in many aspects of our life such as personal care products, medicine, or other beverages.
Importance of the Melting Point of Caffeine
To be used in cosmetics and medicaments, regulations demand that only pharmaceutical-grade caffeine of high purity is used. The simplest way to ensure its quality is to determine the melting point.
Detection of the Melting Point
Usually performed on dry, crystalline, powdered samples, the melting point is measured by monitoring the transmittance during a controlled temperature change. The temperature at which the substance becomes a liquid is the melting point.
Compliance with Pharmacopoeia
The melting point determination of certain pure substances is regulated by national and international pharmacopoeias. Learn how to easily perform the characterization of caffeine in compliance with European and Japanese pharmacopoeias.
