This application note provides a straightforward method to perform the water content in acetone using volumetric Karl Fischer titration using methanol-free K-reagents.
By downloading this application package, you will receive a PDF of the application note as well as the required data for the LabX™ titration software method.
Acetone has wide applications in different segments, such as paints, varnishes, cosmetics, food, explosives, cleaning agents, etc. It is also a key component in pharmaceuticals, as it is used for solubilizing various drugs and as a starting material. The presence of water, even in traces, can alter its properties and sensitivity to certain reactions. Therefore, determining the water content of acetone is essential.
Aldehydes (R-CHO) and ketones (R-CO-R) tend to form acetals and ketals, forming water as a side product when titrated with standard methanol-containing reagents. This leads to an increase in the water content of the samples due to the introduction of water from solvents. Hence, methanol-free K reagents are used to suppress these side reactions as they contain longer-chain alcohol and other organic solvents, thus minimizing side reactions.
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