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Calibration Substances
Melting Point Reference Standards to Verify Instrument Accuracy
Reference standards are substances that enable accurate temperature calibration and adjustment of melting point and dropping point instruments. Each high-purity METTLER TOLEDO calibration substance comes with temperature values that are traceable to primary standards. Calibration substances are provided in the range of 40 – 360 °C and are available as standard or USP reference standards.
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Advantages of Certified Reference Standards
Calibration for Best Performance
With our simple, built-in calibration routines, you can adjust your instrument quickly. Perform a calibration with up to three substances and the instrument automatically calculates the slope and offset values for you.
Certified Temperature Values
Each METTLER TOLEDO high-purity reference substance comes with certified temperature values that are traceable to primary standards (LGC, London).
Full Temperature Range
Certified reference substances are provided in the range of 40 – 360 °C to cover the full temperature range for reliable melting, dropping and softening point measurements.
Useful Related Links
Melting Point Instruments
The Melting Point Excellence portfolio offers five instrument models, with varying measuring techniques, temperature ranges, and sampling capacities. This ensures that you find the perfect solution for your needs. Read more
Melting Point Applications
Our comprehensive application notes support you in performing accurate melting point measurements. They cover the following topics: sample preparation, method creation, and results analysis. Read more
LabX PC Software for Melting Point
LabX™ PC software is used with our melting point instruments to support data integrity and compliance with FDA 21 CFR Part 11. LabX supports step-by-step user guidance to enhance lab productivity. Read more
Good Melting and Dropping Point Practice
Good Melting and Dropping Point Practice is a 5-step program to improve your measuring process. It covers the entire lifecycle of your investment and helps to improve quality while reducing risks and costs. Read more
Melting Point VPac
Ensure efficient and error-free performance verification by temperature calibration with the MP VPac™ Reference Substance Kit, containing pre-filled capillaries of three different standards. Read more
Melting and Dropping Point Standards and Norms
Consult the detailed list of relevant national and international standards and norms for melting, dropping, and softening point determination. Read more
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FAQs
What are the United States Pharmacopeia (USP) requirements for USP reference substances?
USP specifies that the measured melting range must
a) Lie within the specified minimum and maximum temperatures (e.g. 81–83 °C for vanillin), and
b) Not be broader than the specified admissible values (e.g. 1.5 °C for vanillin).
So, the permitted measured melting range for vanillin could be 81.0–82.5, 81.3–82.8 °C etc.