Scientists must work with speed and accuracy to create commercially viable processes at multiple scales. Deliveries are made under stringent regulatory conditions. This is done with limited time and material available for detailed scientific investigations. This complex set of demands means scientists must find innovative methods to ask and answer the big questions. The references and resources below describe how scientists are approaching the this demanding challenge.
Two recently published chemical reaction kinetics studies examples are introduced by researchers at Bristol-Myers Squibb, Scripps, and the University of Wisconsin highlighting how ATR-FTIR spectroscopy was used in conjunction with HPLC and NMR to gain valuable insight, mechanistic understanding, and model validation of the chemical reactions being studied.
This free Citation List presents an extensive list of peer-reviewed publications related to the use of in-situ ReactIR spectroscopy for the advancement of chemical development, providing a valuable resource for researchers, students, and anyone interested in this fascinating field of study.
Spremljanje reakcije na kraju samem s spektroskopijo omogoča znanstvenikom, da vidijo, kaj se dogaja v njihovi kemiji, medtem ko reagira, in omogoča takojšnje spremembe kemijskih pogojev za pospešitev razvoja procesa.
This white paper discusses the root cause of by-product formation in a hydrogenation reaction. and how to avoid by-products during hydrogenation.
Real time, in-situ mid-FTIR reaction monitoring leads to a greater understanding of catalyst activity and robustness. Researchers at the University of Tokyo apply this know-how to a new tandem process for hydroformylation/hydrogenation.
In-situ FTIR spectrometers enable scientists to gain insight into their reactions and processes in a wide range of applications. Optimize reaction variables with inline FTIR instruments.
Reaction Insight Challenges