Table of Contents:
- Introduction
- Background on Solvent Swap Distillations
- Solvent Swap Design Workflow
- Solvent Swap Modeling
- The Solvent Swap Workstation
- Conclusion
- References
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This white paper details a sustainable workflow for optimizing solvent swap distillation in chemical processes. It emphasizes the workflow needed to perform a complete and efficient solvent exchange through dynamic simulation with automated lab experiment data.
The workflow covers steps from initial VLE evaluation and dynamic modeling to tech transfer and production scale-up. A dedicated solvent swap workstation, utilizing automated controls and process analytical technology (PAT), is described to enhance data acquisition and reproducibility. The paper concludes by highlighting the benefits of this integrated approach for improving sustainability and efficiency in chemical manufacturing.
