Microbial Analysis with the 7000RMS

Microbial contamination monitoring in pharmaceutical-grade waters has relied on laboratory-based methods developed over a century ago. These are labor-intensive techniques that require lab personnel to take samples manually from sampling ports. The samples are then cultured on a plate to determine if any colonies form that indicate microbial contamination. This method has a number of potential sources of contamination, even when handled by highly-skilled personnel. This type of contamination can result in false positive readings, which then lead to additional testing expenses, costly investigations and, as a worst case, scrapping of the production batch even though it is not truly contaminated.

An alternative to laboratory-based techniques that is gaining wide acceptance from regulators and the industry, is rapid microbial methods (RMMs). These are real-time, on-line technologies for determining bioburden in a sample.

The 7000RMS is an on-line water bioburden analyzer for real-time measurements of microbial contamination in pharmaceutical waters. This at-line analyzer offers a rapid microbial method solution for controlling water systems.

Real-time Microbial Detection
The 7000RMS delivers continuous monitoring of water with results every two seconds. It requires no sample preparation or incubation period.

Accurate Counting of Microorganisms
Advanced laser-induced fluorescence and Mie scattering technologies are used to count microorganisms present in pharmaceutical grade water systems.

Improves Process Control
The analyzer provides a history of trends in your water system prior to an out-of-specification event, helping to find the root cause of contamination.