This whitepaper aims to provide a comprehensive overview of the role of plate reader-based assays in drug discovery. It will explore their application through the different stages of drug development, highlight the technological advancements that have enhanced their utility, and discuss the future potential of these assays in addressing the evolving demands of pharmaceutical research.
Table of Contents
- Introduction
- The drug discovery pipeline
- The role of plate reader assays in drug discovery
- Protein quantification assays
- Protein-protein and protein-ligand interaction assays
- Enzyme activity assays
- Cell viability and cytotoxicity assay
- ADME profiling assays
- Key features of plate readers in drug discovery
- Technological advancements in plate reader assays
- Conclusions and future perspectives
- References