Microbial Detection Analyzer

Online Water Bioburden Analyzer 7000RMS

Real-time Monitoring of Bioburden in Water

An online water bioburden analyzer is a rapid microbial method for measuring microbial contamination in pharmaceutical grade waters. It offers a real-time microbial monitoring solution, providing continuous results every two seconds for better control of your water system. The 7000RMS rapid bioburden analyzer uses advanced, laser-induced fluorescence and Mie scattering technology to provide immediate detection and quantification of microorganisms.

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Bioburden Analyzer 7000RMS Online

The 7000RMS is an online water bioburden analyzer for real-time measurements of microbial contamination in pharmaceutical waters. This at-line analyzer offers a rapid microbial method solution for controlling your water system.

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30 mL/min – 100 mL/min
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FAQs

How do I measure microbial contamination of water?

There are numerous ways to measure microbial contamination of water, and USP recommends specific ways for pharmaceutical waters.

Traditionally, plate count methods are widely used for releasing water; however, they are prone to error and can take 5-7 days to obtain results. Plate counting also requires the formation of a colony of bacteria on a plate, and hence, the measurement unit is called the 'colony forming unit' or CFU, which estimates the total number of bacteria present in the sample plate.

Another way of measuring microbial contamination in water is through laser-induced fluorescence with a microbial detection analyzer. These analyzers use laser-induced fluorescent technology to measure the total number of cells that are present in the sample volume of water. Systems that use this technology allow at-line, real-time monitoring of microbial contamination in pharmaceutical waters by identifying cells present in the sample water immediately and are reported as auto-fluorescent units (AFUs).

What are auto-fluorescent units?

Auto fluorescent units, or AFUs, are individual microorganisms reported in cells/mL. The 7000RMS illuminates the sample with a laser, resulting in Mie scattering from any particle present in the sample and florescent scattering from metabolites (NADH and riboflavin) present in all bacteria. 

With advanced algorithms and sample processing, the 7000RMS analyzes and reports the number of cells/bacteria in the water sample as AFU.

What is the Microbial Detection Analyzer 7000RMS?

The Microbial Detection Analyzer 7000RMS is a real-time monitoring system designed to detect and quantify microbial contamination. When used in parallel with plate counting, this bioburden analyzer offers a rapid microbial method (RMM) solution for better microbial control of your water system, reducing the risk of releasing contaminated water and improving process control.

The bioburden analyzer uses laser-induced fluorescence and Mie scattering to monitor results continuously every two seconds. This can improve process transparency and help significantly reduce costs.

What are typical applications with the bioburden analyzer?

The 7000RMS online water bioburden analyzer has various applications. It measures microbial contamination in Pharmaceutical-Grade Waters, including Pure Water (PW), Ultrapure Water (UPW), and Water for Injection (WFI), in any industry where they are used.

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